Dyck
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1973 AJP Tofranil
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Should old depressives be forgot? Unable to concentrate, the geriatric depressive tends to take little interest in the affairs around him. His reactions are slow and delayed. He speaks very little. When he does, it's mostly to complain of his insomnia, fatigue, or constipation. Relatives often assume that many of the elderly are this way because they are old. In reality, they may be clinically depressed. One way of relieving depression in the geriatric patient is with Tofranil. It can help alleviate the somatic symptoms that often accompany depression. A good response is generally observed in reactive depressions precipitated by a loss. Because sedation may occur in some persons, especially the elderly, patients should be cautioned against driving a car or operating dangerous machinery. Lower dosages are recommended for elderly patients and adolescents. Remember Tofranil for depressed geriatrics., Imipramine hydrochloride USP, Geigy Pharmaceuticals, Black and white image of older many with hat and jacket on sitting on a bench staring into distance. Image is from the back, so cannot see facial expression. Two page ad. Fine print included.
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1973 AJP Triavil
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The TRIAVIL Potential in the management of moderate to severe anxiety with depression. When time and talk are not enough… The therapist is the primary catalyst for change in the psychotherapeutic relationship. However, when patients suffer from moderate to severe anxiety with depression, there are situations when TRIAVIL can often be a useful adjunct. …TRIAVIL may help. There are three important benefits you may expect when TRIAVIL is part of the treatment program: (1) When symptoms of moderate to severe anxiety or agitation with depression are relieved, the patient may become more accessible and cooperative. (2) As somatic manifestations are controlled, attention may be focused on underlying causative factors. (3) Symptomatic relief may enable the patient to function more effectively in his daily life while your work with the patient progresses. Since it is simpler to remember to take one tablet rather than several (particularly in multiple daily doses), your patients on TRIAVIL will be more likely to take proper doses of the medication. And, of course, economy is an added factor in therapy with TRIAVIL. Tablets TRIAVIL are available in four different combinations affording flexibility and individualized dosage adjustment. Close supervision of patients is essential until satisfactory remission has taken place. Suicide is inherent in any depressive illness so patients should not have easy access to large quantities of the drug. The drug may impair alertness and potentiate the response to alcohol. It should not be used during the acute recovery phase following myocardial infarction or given to patients who have received an MAOI within two weeks. TRIAVIL should be used with caution in glaucoma and in patients prone to urinary retention. It is contraindicated in CNS depression and in the presence of evidence of bone marrow depression. When patients exhibit moderate to marked anxiety or agitation with symptoms of depression, TRIAVIL 4-25, a formulation particularly suited to psychiatric practice when higher doses are required., Perphenazine and pmitriptyline HCI, Merck Sharp & Dohme, Image of man and woman's faces on black background, both look sad/worried. Four page ad. Fine print included.
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1973 AJP Trilafon
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Mirror, mirror on the wall, can this hospitalized schizophrenic relate to herself at all? If the answer is "yes," then she can be helped to relate to others with the adjunctive use of Trilafon brand of perphenazine, NF. A potent phenothiazine to help: maintain alertness level, stabilize behavioral patterns, relieve anxiety/agitation, increase patient response to psychotherapy. Trilafon a major tranquilizer for in hospital control and take home therapy., Perphenazine NF, Schering Corporation, Page 1: women's face in a mirror that has swirled her face and her face looks disoriented. Page 2: same women but now the face looks normal in the mirror. Page 3: pill bottles, medicine dropper, injection. Three page ad. Fine print included.
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1973 AJP Valium
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The clinical study brought closer to your experience. Results of a "small scale" study of Valium (diazepam) and placebo. Sixe patients (3 men and 3 women) with prominent, persistent, high levels of anxiety (Taylor Manifest Anxiety Scale scores above 25) received Valium (diazepam) and placebo under double-blind conditions for six treatment periods of three days each, with a drug-free day between periods. Two dosage levels of Valium, 5 mg and 10 mg t.i.d., and placebo were each administered for two periods. Three methods of rating were employed in this study: physician's rating of symptoms, patient's self-rating, and patient's drug preference. Each patient's three main target symptoms were identified and rated by the physician initially and after each visit. Valium, at both dosage levels, gave higher physician ratings of symptom improvement than placebo, although the changes did not reach statistical significance. The six patients rated their own symptoms in order of severity at the initial interview and graded them daily as to the degree of improvement. In the patient's self-rating changes, both dosage levels of Valium gave higher ratings of improvement than placebo. Also, patients' perference recorded at the end of each week of the trial revealed that Valium (both dosage levels was preferred over placebo to a significant degree. "Small scale" drug trials use methods of observation and patient management similar to those you use in you practive. The physician-investigator assessed Valium (diazepam) just as you might. He treated a small number of persistently anxious patients. He saw them frequently, supporting them, and rated changes in symptoms and had his patients do likewise. He noted that patient's preference for one medication over another. He found that Valium was effective, just as others have in larger, conventional studies, and just as you can find in your practice. If you have not prescribed Valium, select a few overly anxious, psychoneurotic patients with or without associated or secondary depressive symptoms, and give Valium a trial of your own. You'll find it can significantly reduce anxiety and thus may facilitate psychotherapy and make patients more comfortable. Caution patients on Valium against driving or operating machinery. Side effects most commonly reported have been drowsiness, fatigue and ataxia., Diazepam, An MD dressed in a suit, sitting in a chair, reading papers from a clipboard with a pen in one hand. Ad seems to be missing one of the pages.
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1973 AJP Valium
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Predominant Anxiety. Secondary Depressive Symptoms. This psychoneurotic symptom complex often responds to Valium. When you determine that the depressive symptoms are associated with or secondary to predominant anxiety in the psychoneurotic patient, consider Valium in addition to reassurance and counseling, for the psychotherapeutic support it provides. As anxiety is relieved, the depressive symptoms referable to it are also often relieved or reduced. The beneficial effect of Valium is usually pronounced and rapid. Improvement generally becomes evident within a few days, although some patients may require a longer period. Moreover, Valium is generally well tolerated. Side effects most commonly reported are drowsiness, ataxia and fatigue. Caution your patients against engaging in hazardous occupations or driving. Frequently, the patient's symptoms are greatly intensified at bedtime. In such situations, Valium offers an additional advantage: adding an h.s. dose to the b.i.d. or t.i.d. schedule can relieve the anxiety and thus may encourage a more restful night's sleep., Diazepam, Roche Laboratories, Image of woman with very concerned expression, overlayed with strong red tones and underlined text: "Predominant Anxiety" and "Secondary Depressive Symptoms." Two page ad. Fine print included.
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1973 AJP Valium
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Here's what a group of anxious psychoneurotics (most with associated depressive symptoms) looked like untreated: [shows chart of psychiatric evaluation on a modified BPRS, with average scores of 17 patients - out of initial group of 21 patients - in a study for 26 or more days, showing 9 symptoms and scores from 1-5 from not present to extremely severe]. Here's what a group of anxious psychoneurotics (most with associated depressive symptoms) looked like after Valium (diazepam) and psychotherapy. [shows same graph as previous, with results from no treatment and results with treatment put on same chart]. Pretreatment evaluations were compared with those of the second and fourth week of treatment, yielding a cumulative "improvement" score for each patient, symptom and observation interval. A global assessment of the patient's emotional status was also made atr each rating period. In the course of a four-week trial, the investigator studied the effects of Valium (diazepam) in 21 psychoneurotic patients, all with marked anxiety and tension and most with associated depressive symptoms. The Valium daily dosage was 15mg in divided doses, throughout, except for two patients who required a doubling of daily dosage (30mg). The medication supplemented psychotherapy. The clinician rated patients' behavior on a modified Brief Psychiatric Scale before, during, and at the end of treatment. From the individual symptom ratings and the physician's global assessment, it appeared that the concomitant use of Valium and psychotherapy effectively reduced the severity of the anxiety and tension in most patients. The BPRS itself, it should be observed, was employed as a measure of response to therapy. It is not intended to, nor can it, suggest indications for specific medication. Of the 21 patients in the group at the outset, four discontinued treatment some time after the second week because of side effects. Eight patients, including the four who stopped medication, reported one or more side effects: 1 constipation; 7 drowsiness/sleepiness; 1 dry mouth; 3 fatigue-exhaustion; 1 gastrointestinal disturbance; 1 insomnia; 2 nervousness/jitteriness/restlessness; 1 nightmares; 1 unpleasant dreams; 1 vertigo. The patients studied are probably fairly typical of many of your outpatients with marked psychoneuroses. And from the clinical evidence reported over the past nine years, the response to the concomitant use of Valium and psychotherapy seen in this study would also appear to the typical. Valium's beneficial effects can be prompt and pronounced. In recommended dosage, it seldom dulls the sense or interferes with regular activities, although you should caution patients against driving or operating dangerous machinery during therapy. Valium is generally well tolerated: the most common side effects have been drowsiness, ataxia and fatigue. For individualized treatment, three convenient tablet strengths are available: 2 mg, 5mg, and 10mg., Diazepam, Roche Laboratiories, Two graphs (as described in the ad text). Four page ad. Fine print included.
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1973 AJP Valium
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Valium (diazepam) in the context of supportive psychotherapy. To help reduce psychic tension and anxiety. Symptoms of anxiety and tension often appear when the psychiatric patient's self-esteem, individual integrity and security are threatened. The patient may feel out of control, incompetent and insecure when the ego is unable to manage stressful stimuli. If a state of tension prevents the patient from handling problems with calm and logic, the adaptive functioning of the ego may be further impaired. When symptoms of anxiety and tension become excessive, the patient's distress may be incapacitating. In supportive psychotherapy where the goal is to brace the ego and restore its adaptive functioning, acute anxiety and tension must be modified. Your sympathetic recognition of the patient's difficulty in relating disturbing experiences or symptoms fosters a sense of understanding and emotional closeness. Your reassurance, empathy and hope help dissipate feelings of isolation and attenuate anxiety. If these supportive measures are not enough to reduce anxiety and psychic tension to manageable levels, consider Valium (diazepam). Valium, used adjunctively with your supportive measures, can help stabilize your patients by minimizing these excessive symptoms. Whether you use supportive therapy alone or in conjunction with other forms of therapy, you provide that patient with an auxiliary ego which shares the responsibility of coping. Your genuine reassurance and encouragement give the patient confidence and reduce undue stress from external pressures by fortifying ego defenses. If symptoms of excessive anxiety and tension are reduced, the patient can develop a more independent attitude and assume control of the situation. In your treatment of the patient whose symptoms must be modified immediately, the antianxiety and tension-reducing qualities of Valium (diazepam) can be helpful. The adjunctive role of Valium may be significant in aiding the individual in supportive psychotherapy. Valium 10mg can provide prompt effective action in minimizing or eliminating excessive psychic tension and anxiety. Once the symptoms are reduced to a manageable level, Valium (diazepam) may be continued as needed with 2 mg or 5 mg t.i.d. or q.i.d. or discontinued entirely. Valium is generally well tolerated in the usual dosage range. The most frequently reported side effects have been drowsiness, fatigue, and ataxia. Your patients should be cautioned against engaging in hazardous occupations or driving during Valium therapy. When impaired ego function is accompanied by excessive anxiety and psychic tension, the patient needs your supportive help. If the symptoms are incapacitating and must immediately be reduced, consider Valium as an adjunctive psychotherapeutic aid. It may play a small role. But it can be an important one. In the context of supportive psychotherapy, helps reduce psychic tension and anxiety., Diazepam, Roche, Illustration of an MD with his female patient in a psychotherapy session. There is a second illustration with the same depiction. The ad looks like a story book with the "story" written around the illustration. Each paragraph begins with a large bolded letter much like in a story.
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1973 AJP Vivactil
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Today, she managed a smile. (Not long ago, she couldn't stop sobbing). Before he sees that first positive response - however hesitant and tentative - the physician may have to bring into play many different aspects of therapy. Establishing a therapeutic relationship may be the first difficulty as well as the first necessity. Psychotherapy, family and community support, occupational and social counseling, and drug therapy may all have to be enlisted. The characteristically rapid energizing action of VIVACTIL may help establish early therapeutic rapport by lessening the patient's lethargy - often during the first week of medication. VIVACTIL helps elevate mood, usually within the third of fourth week of treatment. Characteristically, the drug has no sedating or tranquilizing properties. (Symptoms such as anxiety or agitation may be aggravated.) Dosage of VIVACTIL must be individualized and patients should be under close medical supervision. For many adult patients with clinically significant depression, 10mg t.i.d. may provide control of symptoms. Others may require as little as 15 mg or as much as 60 mg a day. In elderly patients and adolescents, lower dosages are recommended. In depression, Vivactil helps establish early therapeutic rapport., Protriptyline HCI, Merck Sharp & Dohme, Black and white close up of patient's mouth, smiling. Two page ad. Fine print included.
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1973 AMP Anafranil
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Anafranil exercises amplified action on depressive syndromes of all kinds due to its increased maneuverability in the absence of anxiety during treatment and its intravenous form which allows for additional time in serious cases. Otherwise Anafranil presents a first line choice in the treatment of enuresis. It has been used successfully in the treatment of akinesia resulting from Parkinson's disease. It produces remarkable results in the deficit syndromes of schizophrenics and for those suffering from nervous obsessionally. Finally, Anafranil is frequently effective in the treatment of pain resulting from angina which requires a weaker dose of roughly 10 mg., Laboratoires Geigy, Top 2 thirds of page. Text indicating uses and efficacy. On either side of this column of text, a female face clearly in discomfort (real face on left side, sillhouette of face on right), very dense fine print below. Full page, uses and effectiveness aggressively advertised, *addition of patient should be noted*
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1973 AMP Cogitum
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Neuropsychic asthenia for three stages of life., Merrell Toraude, On a counter, metal cookie cutter type devices arranged to resemble a brain. Brand name in bold orange below. Fine print. Full page
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1973 AMP Concordine
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Fast acting and efficient anti-depressant, Chlorhydrate of Protiptyline, Laboratoires Merck Sharp and Dome, Background is totally black while font is white. Image takes of most of page: girl in her bedroom with her head in her knees, arms wrapped around her knees. Through an open window some abstract shadowy images. Full page, large image, potentially of interest
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1973 AMP Depamide
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Cortical-reticular-limic equilibrium. Psych orthotic with normothymic dominance. Uses: thymic problems both acute and chronic, manic depressive psychosis, recurrent melancholic depression. Troubles in behaviour. Diverse psychotic manifestations. Epilepsy, particularly of the psychiatric variety., Laboratoires Berthier-Derol, Slogan and brand name at top in bold. Text on right indicates uses and dosage. On left, image of some sort of scale that measures "air" - scale is three quarters full. Full page, unable to discern the meaning of the image
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