| Note |
when depression disrupts the day… Norpramin (desipramine hydrochloride tablets NF). For the depressed patient who must remain active during the day. Helps the patient remain calm but active. In addition, begins to improve sleep patterns within one week in some patients. As the depression is relieved, difficulty in falling asleep, restlessness, and early morning awakening diminish, less anticholinergic activity (see warnings). Studies in the laboratory and in normal human subjects have shown that desipramine has less anticholinergic activity than amitriptyline or doxepin. This may mean: less dry mouth, less blurred vision, less urinary retention. Potent blocker of norepinephrine re-uptake. Current evidence suggests depression results from inadequate levels of norepinephrine or serotonin here, at the synaptic cleft. If your patient is unresponsive to treatment with one tricyclic, consider switching to a tricyclic that blocks the re-uptake of a different neurotransmitter. Norpramin offers improved sleep patterns beginning within one week in some patients., norpramin provides less anticholinergic activity than amitriptyline or doxepin, as shown in laboratory studies and studies in normal human subjects. Norpramin is a potent blocker of norepinephrine re-uptake |
