| Note |
when depressive symptoms come in a cluster of blues… adapin (doxepin HCl) helps patients see life in all its colours. Improvements noted at one week. Depressed patients often present with fatigue, anorexia, anxiety, mood swings, loss of interest, and most frequently, early awakening and insomnia. In a summation of 9 clinical studies involving 198 patients, significant clinical improvement was noted after the first week of doxepin treatment. However, optimal antidepressant response may not be evident for two to three weeks. Normalized sleep patterns. In a study of clinically depressed patients with symptoms of insomnia, treatment with doxepin significantly reduced difficulty falling asleep, difficulty staying asleep and frequency of early morning awakening. Low potential for cardiotoxicity. The indigence of tachycardia and hypotension, which have been observed during treatment with tricyclic antidepressants, have been reported infrequently with doxepin. In 452 patients given doxepin, the incidence of tachycardia was 2.88%; in 485 patients, the incidence of hypotension was 2.62%. Now available… 75 mg capsules for h.s. dosage. Adapin… effective single-entity drug with antidepressant and antianxiety effects |
