| Note |
Put depression to rest. The h.s. schedule: provides symptomatic relief throughout the next day. Because of its pharmacokinetic characteristics, Endep (amitriptyline HCl) Roche, provides the same clinical effect over a period of time when given as a single daily h.s. dose or as 1/3 the same dose t.i.d. The h.s. schedule: helps put the side effects in their place. 100 mg. Endep h.s. can provide relief of depression-induced insomnia. Once asleep, the patients are also less likely to notice anticholinergic side effects - such as dry mouth - which reach a peak hours after the h.s. dose. Midnight. Because the sedative effect may impair patients performance during daytime, warn patients not to drive or operate dangerous machinery until the sedative potential has been clearly established. The h.s. schedule: helps maximize patient compliance. According to one investigation, only 40% of patients comply with a t.i.d. drug schedule whereas 93% of patients comply with a one-dose-a-day schedule. An h.s. schedule of Endep (amitriptyline HCl), therefore, should help you maximize patient compliance which, in turn helps ensure prompt recovery. Put depression to rest all day long. 8 am. The 100-mg strength: early signs of progress. Many depressed patients with insomnia and anorexia begin to show improvement during the first week of Endep (amitriptyline HCl) therapy. Patients with symptoms of "neurotic" depression usually improve during the first week, whereas those with "psychotic" depression usually do not imporve until the third week of therapy. However, adequate response may require up to 30 days in both types. Noon. 3pm. The 100-mg strength: the economy and advantage of knowing the score. 100-mg tablets offer potential economy to the patient who requires single doses of 50 mg, 100 mg, or 150 mg. Available as scored tablets, Endep is the only tricyclic antidepressant that can be prescribed in half doses. 7pm. The 100-mg strength: emphasis on individualization of dosage. The 100-mg scored tablet brings to 5 the number of Endep dosage strengths now available as scored tablets: 10 mg, 25 mg, 50 mg, 75 mg, and 100 mg. With 100mg Endep amitriptyline HCl/Roche. The only tricyclic antidepressant with scored tablets. |
