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Titles |
1973 British Journal of Psychiatry Orap |
Related Item |
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Genre |
medicine |
Genre |
medicines (psychiatric) |
Identifier |
BJP1973Jan_Mar28 |
Note |
Her lonely world is often peopled by strange and frightening happenings.Delusions, hallucinations, withdrawal, the bizarre symptoms that haunt the schizophrenic are now commonly associated with an excess of cerebral dopamine. Selective blockade of this neurotransmitter by Orap (pimozide) offers the psychiatrist a new dimension in the treatment of schizophrenia. Now the inactive and apathetic schizophrenic can be treated with only a remote risk of noradrenaline blockade and hence undesired sedation and stupor can be avoided. With little or no Parkinsonian side effect liability Orap is well accepted by patients. They become amenable and co-operative during rehabilitation and are able to undertake tasks requiring mental alertness. Once-a-day Orap. "especially indicated for schizophrenics who are inactive and apathetic and for these patients it appears to be superior to previously available neuroleptics." |
Abstract |
Pimozide, Janssen Pharmaceuticals, A black-and-white photo of a women sitting on a park swing, with the ground around her wet as if it is raining. |