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| Titles |
1993 Canadian Journal of Psychiatry Loxapac |
| Related Item |
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| Genre |
medicine |
| Genre |
medicines (psychiatric) |
| Identifier |
cjp1993feb_mar_apr_may9 |
| Note |
When aggressive behavior in the elderly is the problem. "Regardless of etiology the physician is often in the position of having to intervene in a potentially dangerous situation. Stabilizing the person's behavior must be the first concern." Loxapac may be particularly beneficial for elderly patients with aggressive behavior. Loxapac controls aggressive behavior in both elderly patients and patients suffering from acute schizophrenia. Loxapac produces significant improvement of psychopathology and social functioning in elderly patients compared to haloperidol. "When treating these [elderly] patients the physician should choose as specific acting a drug as possible, avoiding those with a wide range of actions and resulting side-effects." Loxapac has fewer extrapyramidal side-effects than haloperidol. Loxapac also has less sedation, orthostatic hypotension and anticholinergic side-effects than lower potency neuroleptics, chlorpromazine and thioridazine. Dosage flexibility for elderly patients. Lower initial doses and more gradual titration are recommended for elderly and debilitated patients. Loxapac effective control of aggression with moderate side-effects. |
| Abstract |
Loxapine Succinate, Lederle, A man with a cactus as his head, is pictured screaming with his mouth open, and punching down on the dinner table. There are others in the image who look very frightened. |
