1973 IJP Sarotena

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Titles	1973 IJP Sarotena
Related Item
Genre	medicine
Identifier	IJP57
Note	Enuresis 'sure of dry nights'. Sarotena. "Analysis of the data from the cross-over trial by the Wilcoxon matched-pairs signed ranks test showed a clear superiority of Amitryptyline over the placebo in decreasing the frequency of nocturnal enuresis." AMITRIPTYLINE in the treatment of Enuresis in children. A double blind controlled clinical study of Amitriptyline and placebo in the management of children with enuresis was carried out. The drug administered for six weeks in a dose of 25 to 50 mg given at bed time was found superior to placebo. The finding was statistically significant.
Abstract	Amitriptyline Hydrochloride, Kembiotic Collaborators, Young male child crying or distressed because there is a pile of urine at the bottom of his bed. *Notable that clinical study using drug and placebo found statistically significant results for use of drug.