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| Titles |
1981 British Journal of Psychiatry Norval |
| Related Item |
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| Genre |
medicine |
| Genre |
medicines (psychiatric) |
| Identifier |
bjp1981jan_mar21 |
| Note |
Tricyclics help the depression but what are they doing to the heart? Amitriptyline overdosage: "Lead I of the electrocardiogram taken on admission shows…supraventricular tachycardia in the last three complexes of the tracing…preceded by nodal rhythm and two ventricular ectopic beats. While tricyclic antidepressants help relieve depression, they also have a number of unwanted side-effects and can be cardiotoxic even at therapeutic dosage. Cardiac arrhythmia following tricyclic overdosage can be fatal. Norval is as effective as amitriptyline but does not produce the adverse "tricyclic" cardiovascular effects. Therefore Norval may be given with confidence even to patient with pre-existing heart disease. Norval relieves depression but leaves the heart alone. |
| Abstract |
Mianserin Hydrochloride, Bencard, An ECG tracing. |
